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Department of Medicinal Chemistry · Deccan Institute of Scienceraolab@example.edu
RLRao Lab

Department of Medicinal Chemistry · Deccan Institute of Science

From target to medicine

Small molecules that beat drug-resistant bacteria, designed, made and tested in one lab.

Our researchJoin the lab
  1. 014Research programmes
  2. 0218Publications
  3. 0313Scientists
  4. 048News
  5. 053Open positions

We are chemists, biologists and data scientists working on new antibiotics. Drug-resistant infections already kill more than a million people a year, and few new drugs are on the way.

We combine structure-based design, high-throughput screening and machine learning, and we share our compounds and data openly.

Research

All programmes
  1. PRG-01Antibiotics for resistant bacteriaNew classes of antibiotics against the bacteria that resist every drug we have.
  2. PRG-02Structure-based designCrystal structures and simulations guide each molecule we make.
  3. PRG-03High-throughput screeningRobotic assays that test 100,000 compounds a week against live bacteria.
  4. PRG-04AI for medicinal chemistryMachine-learning models that predict which molecules will work, and which will be safe.

Selected publications

All publications

News

All news
Our new class of antibiotics is published in NaturePriya’s compounds kill drug-resistant bacteria in a way no approved drug does. Congratulations to everyone involved!Welcome, Jonah and Ana!Two new members join the lab this semester: Jonah Brooks (PhD) and Ana Souza (MSc).Ananya Rao receives the Swarnajayanti FellowshipThe fellowship supports five years of work on antibiotics for resistant infections.

We’re recruiting

PhD positions in antibiotic discovery · Postdoctoral researcher: structural biology · Summer research internships

See open positions

Funding & affiliations